DP3004 APC11 antibody

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Rabbit anti Human, Mouse APC11


Product Description for APC11

Rabbit anti Human, Mouse APC11.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for APC11

Product Category Primary Antibodies
Quantity 0.5 mg
Presentation Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

A peptide from C-terminus of the human APC11 (aa 76-84).
Application Western blot. Recommended positive control: HeLa, NIH-3T3 Cells.
Background APC11 is a subunit of the anaphase-promoting complex (APC). This protein is homologous to the two highly conserved RING finger proteins ROC1 and ROC2. APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. Combinations of ROC/APC11 and cullin proteins potentially constitute a wide variety of ubiquitin ligases.
Concentration 1 mg/ml
General Readings
  1. Ohta T et al.,(1999) Oncogene
Storage Store at 2-8°C for up to one month or in aliquots at -20°C for longer. Avoid repeated freeze thaw cycles!
Shelf life: one year from despatch.
Protein A affinity purified immunoglobulin fraction
Buffer System:
10mM PBS with 0.09% sodium azide as preservative and 0.2% BSA as stabilizer.
Highly specific fpr APC11. No crossreactivities with other family members observed so far. Mol. Wt. of Antigen: 10 kD
Human and Mouse.

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