TA332099 ASAP2 / DDEF2 antibody

Rabbit Polyclonal Anti-ASAP2 Antibody

See related secondary antibodies

Search for all "ASAP2 / DDEF2"

50 µg / €360.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish ASAP2 / DDEF2

Product Description for ASAP2 / DDEF2

Rabbit anti Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish ASAP2 / DDEF2.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for ASAP2 / DDEF2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Arf-GAP with SH3 domain ANK repeat and PH domain-containing protein 2, Development and differentiation-enhancing factor 2, KIAA0400, PAG3, PAP, Paxillin-associated protein with ARF GAP activity 3, Pyk2 C-terminus-associated protein
Presentation Purified
Reactivity Can, Eq, Hu, Ms, Por, Rb, Rt, Ze
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
O43150
Immunogen:
The immunogen for Anti-ASAP2 Antibody is: synthetic peptide directed towards the N-terminal region of Human ASAP2. Synthetic peptide located within the following region: LSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQ.
GeneID:
8853
Application WB
Background This gene encodes a multidomain protein containing an N-termil alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-termil Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kise 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-termil proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport.
Format
Buffer System:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for ASAP2 / DDEF2 (4 products)

Catalog No. Species Pres. Purity   Source  

ASAP2 / DDEF2

ASAP2 / DDEF2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ASAP2 / DDEF2

ASAP2 / DDEF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for ASAP2 / DDEF2 (3 products)

Catalog No. Species Pres. Purity   Source  

ASAP2 overexpression lysate

ASAP2 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.

DDEF2 293T Cell Transient Overexpression Lysate(Denatured)

DDEF2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PAG3 / ASAP2 Lysate

Western Blot: PAG3 Lysate [NBL1-09768] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for ASAP2.
  Novus Biologicals Inc.
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