50100002 ASH1 antibody

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Rabbit anti Drosophila ASH1


Product Description for ASH1

Rabbit anti Drosophila ASH1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for ASH1

Product Category Primary Antibodies
Quantity 50 µg
Synonyms anti-ASH1L antibody, anti-Absent antibody, anti-KMT2H. antibody, anti-SH1 antibody, anti-Small antibody, anti-or homeotic-like 1 antibody
Presentation Aff - Purified
Reactivity Dros
Applications E, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
In vivo generated recombinant protein fragment
Background Trithorax group (TrxG) protein that has histone methyltransferase activity. Specifically trimethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation. May also trimethylate H3 'Lys-9' and H4 'Lys-20'; however the relevance of this activity is unclear in vivo. TrxG protein are generally required to maintain the transcriptionally active state of homeotic genes throughout development. Does not act as a coactivator required for transcriptional activation, but specifically prevent inappropriate Polycomb Group (PcG) silencing of homeotic genes in cells in which they must stay transcriptionally active. Binds non-coding RNAs of trithorax response element (TRE), leading to its recruitment to the corresponding TRE in chromatin.
Storage Store at -20C. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Aff - Purified
Gene ID 40133

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