NBP1-30071 ATF7 antibody

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Rabbit anti Human ATF7

Product Description for ATF7

Rabbit anti Human ATF7.
Presentation: Aff - Purified
Product is tested for Immunoprecipitation, Western blot / Immunoblot.

Properties for ATF7

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms ATF-7, ATF-A, ATFA, Activating transcription factor 7
Presentation Aff - Purified
Reactivity Hu
Applications IP, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
Application immunoprecipitation, Western Blot, This antibody is useful in Immunoprecipitation and Western Blot., immunoprecipitation 10 to 15 mcg/mg lysate, Western Blot 1:2,000 to 1:10,000
Background Eukaryotic gene transcription is regulated by sequence-specific transcription factors, which bind modular cis acting promoter and enhancer elements. The cAMP response element (CRE) consists of the palindromic octanucleotide TGACGTCA. There are several CRE binding proteins within the ATF/CREB family, including CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. A novel basic leucine zipper (bZIP) protein, designated ATF-7, is closely related to members of the ATF/CREB family of bZIP proteins, with highest homology to ATF-4. ATF-7 physically interacts with the PRL-1 protein-tyrosine phosphatase (PTPase), which is a predominately nuclear, farnesylated PTPase. ATF-7 homodimers bind specifically to CRE elements. ATF-7 is expressed in a number of different tissues and is expressed in association with differentiation. ATF-7 and PRL-1 interact with each other through the bZIP region of ATF-7 and the phosphatase domain of PRL-1. In addition, PRL-1 is able to dephosphorylate ATF-7 in vitro.
Concentration 1 mg/ml
Storage Store at 4C. Do not freeze.
Affinity purified
Buffer System:
0.09% Sodium Azide
Affinity purified
Aff - Purified
maps to a region between residue 444 and 494 of human activating transcription factor 7 using the numbering given in entry CAA40483.1,
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