AP08052PU-S ATM antibody

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50 µg / €230.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse ATM

AP08052PU-S

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  • AP08052PU-S

Product Description for ATM

Rabbit anti Human, Mouse ATM.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for ATM

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms A-T mutated, ATDC, Ataxia telangiectasia mutated, Serine-protein kinase ATM, TEL1, TELO1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q13315
Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human ATM around the phosphorylation site of Serine 1981 (E-G-SP-Q-S).
GeneID:
472
Application Western Blot: 1/500-1/1000.
Immunofluorescence: 1/100-1/200.
Background ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
Concentration 1.0 mg/ml
General Readings
  1. Gupta A. et al. (2005) Mol Cell Biol. 25(12): 5292-5305.
  2. Bernstein JL. et al. (2002) Breast Cancer Res. 4(6): 249-252.
  3. Silverman J. et al. (2004) Genes Dev. 18(17): 2108-2119.
  4. Nakada D. et al. (2003) Nucleic Acids Res. 31(6): 1715-1724.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity Chromatography using epitope-specific immunogen
Buffer System:
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse
Specificity
Specificity:
ATM Antibody AP08052PU detects endogenous levels of total ATM protein.
Gene ID 472
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for ATM (5 products)

Catalog No. Species Pres. Purity   Source  

ATM

ATM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ATM

ATM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ATM

ATM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ATM

ATM Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

ATM

ATM Human
  Abnova Taiwan Corp.
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