discontinued

AP07481PU-N Aurora kinase A pThr288 antibody

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Rabbit anti Human Aurora kinase A

Product Description for Aurora kinase A

Rabbit anti Human Aurora kinase A.
Properties: pThr288
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Aurora kinase A

Product Category Primary Antibodies
Target Category
Quantity 50 µl
Synonyms AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O14965
Immunogen:
KLH conjugated Synthetic peptide
GeneID:
6790
Remarks:
Antigen Modification: pThr288
Property pThr288
Application Western Blot.
Immunohistochemistry on Paraffin Sections: 1/50.
Background ARK1, an Aurora/IPL1-like protein kinase, functions in centrosome separation, duplication, and maturation and in bipolar spindle assembly and stability. The protein has been shown to localize to centrosomes in S phase as soon as centrioles have been duplicated, and to be degraded in early G1. ARK1 phosphorylation is induced by okadaic acid treatment in vivo. Activated ARK1 has been shown to phosphorylate the spindle apparatus-associated protein, TPX2, and it is believed to be targeted to the spindle apparatus by this protein. At least three alternative splice forms have been reported; however, the alternative splice sites are located in the 5’-untranslated region and appear to have no effect on protein translation. ARK1 has been identified as an oncogene that is overexpressed in several types of solid tumors and tumor cell lines, including those from breast and colon. Additionally, overexpression of ARK1 has been implicated in mechanisms leading to mitotic spindle aberrations, aneuploidy, and genomic instability.
Concentration 0.21 mg/ml
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated reezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity Chromatography.
Buffer System:
Phosphate-buffered solution, pH 7.2 containing 0.09% Sodium Azide and 50% Glycerol
State:
Liquid purified Ig fraction.
Aff - Purified
Specificity
Specificity:
This antibody reacts to Aurora-Related Kinase 1 (ARK1/AURKA).
Species:
Human.
Gene ID 6790
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for Aurora kinase A (19 products)

Catalog No. Species Pres. Purity   Source  

Aurora kinase A (transcript variant 6)

Aurora kinase A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Aurora kinase A (transcript variant 5)

Aurora kinase A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Aurora kinase A (transcript variant 1)

Aurora kinase A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Aurora kinase A (transcript variant 3)

Aurora kinase A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

Aurora kinase A (1-403, His-tag)

Aurora kinase A Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €750.00
  OriGene Technologies GmbH

Aurora kinase A (1-403, His-tag)

Aurora kinase A Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €300.00
  OriGene Technologies GmbH

Aurora kinase A

Aurora kinase A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human Purified
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human Purified
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human
  Abnova Taiwan Corp.

Aurora kinase A

Aurora kinase A Human
  Abnova Taiwan Corp.

Positive controls for Aurora kinase A (10 products)

Catalog No. Species Pres. Purity   Source  

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

AURKA overexpression lysate

AURKA overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

Aurora A Lysate

Western Blot: Aurora A Lysate [NBL1-07855] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for AURKA Protein
  Novus Biologicals Inc.

Aurora A Lysate

Western Blot: Aurora A Lysate [NBL1-07856] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for AURKA Protein
  Novus Biologicals Inc.

Aurora A Lysate

Western Blot: Aurora A Lysate [NBL1-07857] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for AURKA Protein
  Novus Biologicals Inc.
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