AP01307PU-N BAI1 antibody

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0.1 mg / €350.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse BAI1

AP01307PU-N

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  • AP01307PU-N

Product Description for BAI1

Rabbit anti Human, Mouse BAI1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Properties for BAI1

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms BAI-1, Brain-specific angiogenesis inhibitor 1
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 174 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O14514
Immunogen:
Synthetic peptide, corresponding to amino acids 711-760 of Human BAI-1.
GeneID:
575
Application Western Blot: 1/500-1/1000.
Immunofluorescence: 1/50-1/200.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Background Brain-specific angiogenesis inhibitors, including BAI-1, BAI-2 and BAI-3, are integral membrane proteins belonging to the G protein-coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-1 protein is specifically expressed in the brain and found to localize to the cytoplasm and membrane in neuronal cells of the cerebral cortex. Reduced expression of BAI-1 in some glioblastoma cell lines and cancer tissues implicates the functional role of BAI-1 as an inhibitor of angiogenesis. The exact mechanisms underlying BAI-1 anti-angiogenetic activity are still being investigated. BAI-1 may be involved in mediating the p53 signal in suppression of glioblastoma, as well as in cell adhesion and signal transduction. Additional research shows an inverse correlation with vascularization and BAI-1 expression in both colorectal carcinomas and pulmonary adenocarcinomas.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen
Buffer System:
Phosphate buffered saline (PBS), pH~7.2
Preservatives:
0.05% Sodium Azide
State:
Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse and Rat.
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of BAI-1 protein.(region surrounding Gln732)
Gene ID 575

Accessory Products

Proteins and/or Positive Controls

Positive controls for BAI1 (1 products)

Catalog No. Species Pres. Purity   Source  

ADGRB1 overexpression lysate

ADGRB1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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