TA328137 BBS4 antibody

Mouse monoclonal anti-BBS4 antibody (Center)

See related secondary antibodies

Search for all "BBS4"

0.4 ml / €410.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human, Mouse, Rat BBS4 1292CT845.130.218

Product Description for BBS4

Mouse anti Human, Mouse, Rat BBS4 1292CT845.130.218.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for BBS4

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Bardet-Biedl syndrome 4 protein
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Monoclonal
Clone 1292CT845.130.218
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96RK4
Immunogen:
This BBS4 antibody is generated from a mice immunized with a recombinant protein between 1-240 amino acids from human BBS4.
GeneID:
585
Isotype control AM03095PU-N, SM10P (for use in human samples), SM20P (for use in rat samples)
Application WB: 1:1000
Background The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.
Format
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Buffer System:
PBS with 0.09% (W/V) sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for BBS4 (4 products)

Catalog No. Species Pres. Purity   Source  

BBS4

BBS4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

BBS4

BBS4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BBS4

BBS4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BBS4

BBS4 Human
  Abnova Taiwan Corp.

Positive controls for BBS4 (2 products)

Catalog No. Species Pres. Purity   Source  

BBS4 Lysate(Denatured)

BBS4 Lysate(Denatured)
  Abnova Taiwan Corp.

BBS4 Lysate

Western Blot: BBS4 Lysate [NBL1-07929] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for BBS4 Protein
  Novus Biologicals Inc.
  • LinkedIn