SP2167P BCAP31 / BAP31 antibody

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0.1 mg / €460.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat BCAP31 / BAP31

SP2167P

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  • SP2167P

Product Description for BCAP31 / BAP31

Rabbit anti Human, Mouse, Rat BCAP31 / BAP31.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for BCAP31 / BAP31

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P51572
Immunogen:
A 17 amino acid peptide located near the centre of human BAP31
GeneID:
10134
Application Western blot (0.5 - 1 µg/ml, detects a band of approximately 28 kDa in rat lung cell lysates).
Immunohistochemistry on paraffins sections.
Background BAP31 is a 28 kDa conserved type III integral membrane protein of the Endoplasmic Reticulum (ER), containing two caspase cleavage sites within its cytosolic domain.
BAP31 appears to be a multi-functional ER-associated transport protein which was originally identified through its association with membrane IgD in B lymphocytes. Several proteins have since been shown to associate with BAP31, including the Beta2 integrin receptor CD11b/CD18, and nonmuscle gamma-actin and myosin B heavy chain. BAP31 has become a focus area for apoptosis studies due to its association with Bcl-2 and cleavage by initiator caspases including caspase 1 and 8. Cleavage of BAP31 generates a membrane-integrated p20 fragment which is itself a potent inducer of apoptosis when expressed ectopically.
Concentration 1.0 mg/ml
General Readings
  1. Kim KM, Adachi T, Nielsen PJ, Terashima M, Lamers MC, Köhler G, et al. Two new proteins preferentially associated with membrane immunoglobulin D. EMBO J. 1994 Aug 15;13(16):3793-800. PubMed PMID: 8070407. (Free PMC Article available)
  2. Ng FW, Nguyen M, Kwan T, Branton PE, Nicholson DW, Cromlish JA, et al. p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum. J Cell Biol. 1997 Oct 20;139(2):327-38. PubMed PMID: 9334338. (Free PMC Article available, 7 images available)
  3. Ducret A, Nguyen M, Breckenridge DG, Shore GC. The resident endoplasmic reticulum protein, BAP31, associates with gamma-actin and myosin B heavy chain. Eur J Biochem. 2003 Jan;270(2):342-9. PubMed PMID: 12605685.
  4. Zen, K. et al. (2004) Association of BAP31 with CD11b/CD18. J. Biol. Chem. 279: 44924-44930.
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography
Buffer System:
Phosphate buffered saline, 0.02 % Sodium Azide (NaN3)
State:
Liquid Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody recognises an epitope within the internal region of BAP31 (B cell receptor-associated protein 31).
Species:
Human, Mouse, Rat.
Gene ID 10134

Accessory Products

Proteins and/or Positive Controls

Proteins for BCAP31 / BAP31 (7 products)

Catalog No. Species Pres. Purity   Source  

BCAP31 / BAP31 (transcript variant 2)

BCAP31 / BAP31 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

BCAP31 / BAP31 (transcript variant 3)

BCAP31 / BAP31 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

BCAP31 / BAP31 (transcript variant 1)

BCAP31 / BAP31 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

BCAP31 / BAP31

BCAP31 / BAP31 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

BCAP31 / BAP31

BCAP31 / BAP31 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

BCAP31 / BAP31

BCAP31 / BAP31 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BCAP31 / BAP31

BCAP31 / BAP31 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for BCAP31 / BAP31 (5 products)

Catalog No. Species Pres. Purity   Source  

BCAP31 / BAP31 Lysate(Denatured)

BCAP31 / BAP31 Lysate(Denatured)
  Abnova Taiwan Corp.

BCAP31 Lysate

Western Blot: BCAP31 Lysate [NBL1-07934] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for BCAP31 Protein
  Novus Biologicals Inc.

BCAP31 overexpression lysate

BCAP31 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

BCAP31 overexpression lysate

BCAP31 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

BCAP31 overexpression lysate

BCAP31 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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