TA306134 Bcl-2-like 10 antibody

Rabbit Polyclonal Bcl-B Antibody

See related secondary antibodies

Search for all "Bcl-2-like 10"

0.1 mg / €371.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human Bcl-2-like 10

TA306134

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  • TA306134

Product Description for Bcl-2-like 10

Rabbit anti Human Bcl-2-like 10.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Bcl-2-like 10

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Anti-apoptotic protein NrH, Apoptosis regulator Bcl-B, BCL2L10, BCLB, Bcl-B, Bcl2-L-10, NrH
Presentation Aff - Purified
Reactivity Hu
Applications E, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9HD36
Immunogen:
Bcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B. (AP30130CP-N)
GeneID:
10017
Add. information Blocking peptide available: blocking peptide (AP30130CP-N)
Application ELISA.
Western Blot: Bcl-B antibody can be used for the detection of Bcl-B at 1 - 2 μg/ml.
Immunocytochemistry.
Background Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.
General Readings
  1. Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene. 2003 Nov 24;22(53):8590-607. PubMed PMID: 14634621.
  2. Heiser D, Labi V, Erlacher M, Villunger A. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp Gerontol. 2004 Aug;39(8):1125-35. PubMed PMID: 15288687.
  3. Ke N, Godzik A, Reed JC. Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak. J Biol Chem. 2001 Apr 20;276(16):12481-4. Epub 2001 Feb 21. PubMed PMID: 11278245.
  4. Song Q, Kuang Y, Dixit VM, Vincenz C. Boo, a novel negative regulator of cell death, interacts with Apaf-1. EMBO J. 1999 Jan 4;18(1):167-78. PubMed PMID: 9878060. (Free PMC Article available)
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
This antibody reacts to Bcl-B.
Species:
Human.

Accessory Products

Proteins and/or Positive Controls

Proteins for Bcl-2-like 10 (6 products)

Catalog No. Species Pres. Purity   Source  

Bcl-2-like 10 (1-172, His-tag)

Bcl-2-like 10 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  OriGene Technologies GmbH

Bcl-2-like 10 (1-172, His-tag)

Bcl-2-like 10 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

Bcl-2-like 10

Bcl-2-like 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Bcl-2-like 10

Bcl-2-like 10 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Bcl-2-like 10

Bcl-2-like 10 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 10

Bcl-2-like 10 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Bcl-2-like 10 (1 products)

Catalog No. Species Pres. Purity   Source  

BCL2L10 293T Cell Transient Overexpression Lysate(Denatured)

BCL2L10 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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