TA306135 Bcl-2-like 14 (C-term) antibody

Rabbit Polyclonal Bcl-G Antibody

See related secondary antibodies

Search for all "Bcl-2-like 14"

0.1 mg / €415.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Bcl-2-like 14

TA306135

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  • TA306135
  • TA306135

Product Description for Bcl-2-like 14

Rabbit anti Human, Mouse, Rat Bcl-2-like 14.
Properties: (C-term)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for Bcl-2-like 14

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Apoptosis facilitator Bcl-2-like protein 14, BCL2L14, BCLG, Bcl-G, Bcl2-L-14
Presentation Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BZR8
Immunogen:
15 amino acids near the C-terminus of human Bcl-G
GeneID:
79370
Property C-term
Application ELISA.
Western blot: 2.5 to 5 µg/ml.
Immunohistochemistry on paraffin sections.
Positive control: U937 Cell Lysate; Mouse Testis Tissue Lysate.
Background Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain (reviewed in 1 and 2). BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G (3). The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein (3).
General Readings
  1. Cory S, Huang DC, Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene. 2003 Nov 24;22(53):8590-607. PubMed PMID: 14634621.
  2. Heiser D, Labi V, Erlacher M, Villunger A. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp Gerontol. 2004 Aug;39(8):1125-35. PubMed PMID: 15288687.
  3. Guo B, Godzik A, Reed JC. Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. J Biol Chem. 2001 Jan 26;276(4):2780-5. Epub 2000 Oct 27. PubMed PMID: 11054413.
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Ion exchange chromatography purified
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
Specificity
Specificity:
This antibody detects Bcl-2-like 14 at C-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for Bcl-2-like 14 (4 products)

Catalog No. Species Pres. Purity   Source  

Bcl-2-like 14 (transcript variant 1)

Bcl-2-like 14 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Bcl-2-like 14 (transcript variant 4)

Bcl-2-like 14 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Bcl-2-like 14

Bcl-2-like 14 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 14

Bcl-2-like 14 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for Bcl-2-like 14 (4 products)

Catalog No. Species Pres. Purity   Source  

BCL2L14 overexpression lysate

BCL2L14 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

BCL2L14 overexpression lysate

BCL2L14 overexpression lysate
0.1 mg / €315.00
  OriGene Technologies, Inc.

Bcl-2-like 14 Lysate(Denatured)

Bcl-2-like 14 Lysate(Denatured)
  Abnova Taiwan Corp.

Bcl G Lysate

Western Blot: Bcl G Lysate [NBL1-07949] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for BCL2L14. Protein
  Novus Biologicals Inc.
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