AP55717PU-S Bcl-2-like 8 pSer91/128 antibody

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50 µl / €270.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat Bcl-2-like 8

AP55717PU-S

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  • AP55717PU-S

Product Description for Bcl-2-like 8

Rabbit anti Human, Mouse, Rat Bcl-2-like 8.
Properties: pSer91/128
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Bcl-2-like 8

Product Category Primary Antibodies
Target Category
Quantity 50 µl
Synonyms BAD, BBC6, BCL2L8, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, Bcl2-L-8
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Molecular weight 22 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q92934
Immunogen:
Peptide sequence around phosphorylation site of Serine 91 (E-P-S(p)-P-F) derived from Human BAD or Serine 128 (E-P-S(p)-P-F) derived from Mouse BAD (KLH-conjugated)
GeneID:
572
Property pSer91/128
Application Western blot: 1:500~1:1000.
Immunohistochemistry on paraffin sections: 1:50~1:100.
Background The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Concentration 1.0 mg/ml
General Readings
  1. Wang HG, Rapp UR, Reed JC. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell. 1996 Nov 15;87(4):629-38. PubMed PMID: 8929532.
  2. Ottilie S, Diaz JL, Horne W, Chang J, Wang Y, Wilson G, et al. Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins. J Biol Chem. 1997 Dec 5;272(49):30866-72. PubMed PMID: 9388232.
  3. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. PubMed PMID: 15489334. (Free PMC Article available, 2 images available)
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse, Rat
Specificity
Specificity:
The antibody detects endogenous levels of BAD only when phosphorylated at serine 91/ serine 128.

Accessory Products

Proteins and/or Positive Controls

Proteins for Bcl-2-like 8 (15 products)

Catalog No. Species Pres. Purity   Source  

Bcl-2-like 8 (transcript variant 1)

Bcl-2-like 8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Bcl-2-like 8 (full length, N-term HIS tag, transcript variant 2)

Bcl-2-like 8 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Bcl-2-like 8

Bcl-2-like 8 Human Purified E. coli
  Acris Antibodies GmbH

Bcl-2-like 8

Bcl-2-like 8 Human Purified E. coli
  Acris Antibodies GmbH

Bcl-2-like 8

Bcl-2-like 8 Human Purified E. coli
  Acris Antibodies GmbH

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Bcl-2-like 8

Bcl-2-like 8 Human
  Abnova Taiwan Corp.

Positive controls for Bcl-2-like 8 (1 products)

Catalog No. Species Pres. Purity   Source  

Bad Lysate

Western Blot: Bad Lysate [NBL1-07900] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for BAD. Protein
  Novus Biologicals Inc.
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