NBP1-28567 Bcl2 antibody

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Mouse anti Mouse, Rat Bcl2 10C2


Product Description for Bcl2

Mouse anti Mouse, Rat Bcl2 10C2.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Bcl2

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms anti-Apoptosis regulator Bcl 2 antibody, anti-Apoptosis regulator Bcl2 antibody, anti-B cell CLL/lymphoma 2 antibody, anti-B cell leukemia/lymphoma 2 antibody, anti-B cell lymphoma 2 antibody, anti-BCL2 protein antibody, anti-Bcl 2 antibody, anti-Bcl2 antibody
Presentation Purified
Reactivity Ms, Rt
Applications E, WB
Clonality Monoclonal
Clone 10C2
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

KLH-conjugated peptide corresponding to 61-76 amino acid sequence of murine Bcl-2 (1)
Isotype control AM03095PU-N, SM20P (for use in rat samples)
Application ELISA, Western Blot, ELISA and Western Blot, ELISA , Western Blot ≤ 1 ug/ml
Background Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. (2) It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. (3) Bcl-2 is a widely studied protein that has been shown to be a potent inhibitor of programmed cell death. It has been localized to the outer mitochondrial membrane, perinuclear membrane, and endoplasmic reticulum. Bcl-2 is expressed in memory and resting, or other long-lived lymphoid cells, follicular mantle cells, medullary thymocytes, and lymphomas. Germical center cells and cortical thymocytes are negative for Bcl-2. Upregulation of Bcl-2 prevents or delays apoptosis induced by a variety of stimuli, including growth factor deprivation, γ-irradiation, glucocorticoids, and chemotherapeutic agents. During lymphoid development, expression of the Bcl-2 protein appears to be regulated in a stage-specific manner, and is thought to be a survival signal for positive selection. The monoclonal antibody 10C2 reacts with both mouse and rat Bcl-2. (1)
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
No Preservative
IgG purified
Mouse and rat Bcl-2 (Mr 26 kDa)
Mouse, Rat

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