NBP1-28559 BCL2L1 (7B2.5) antibody

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50 µg / €360.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human BCL2L1 (7B2.5) 7B2.5

Product Description for BCL2L1 (7B2.5)

Mouse anti Human BCL2L1 (7B2.5) 7B2.5.
Presentation: Purified
Product is tested for Frozen Sections, Flow Cytometry, Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot.

Properties for BCL2L1 (7B2.5)

Product Category Primary Antibodies
Quantity 50 µg
Synonyms anti-Apoptosis regulator Bcl X antibody, anti-Apoptosis regulator BclX antibody, anti-B cell lymphoma 2 like antibody, anti-BCL XL/S antibody, anti-BCL2L antibody, anti-BCLX antibody, anti-Bcl 2 like 1 protein antibody, anti-Bcl X antibody, anti-Bcl xL antibody, anti-Bcl xS antibody, anti-Bcl2 Like 1 antibody, anti-Bcl2 related gene antibody, anti-Bcl2l1 antibody, anti-BclXL antibody, anti-BclXs antibody, anti-DKFZp781P2092 antibody
Presentation Purified
Reactivity Hu
Applications C, F, IP, P, WB
Clonality Monoclonal
Clone 7B2.5
Host Mouse
Isotype IgG3
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Recombinant Bcl-xS
Isotype control AM03097PU-N
Add. information Research Areas: Cancer
Application flow cytometry / FACS analysis, immunohistochemistry, immunoprecipitation, Western Blot, Flow cytometry / FACS analysis, Immunoprecipitation, Western Blot and Immunohistochemistry, flow cytometry / FACS analysis ≤ 3 ug/1^6 cells, immunohistochemistry , immunoprecipitation , Western Blot
Background Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. (1) It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. (2) Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis (3,4), while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. (5-8) Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. (9-13) In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2, (5,14) other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity. (15,16) Mab 7B2.5 recognizes both human and rodent Bcl-xL. (17)
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
No Preservative
IgG purified
Human Bcl-xL (Mr 29 kDa)

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