AP55922PU-S BCR pTyr360 antibody

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50 µg / €270.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse BCR

Product Description for BCR

Rabbit anti Human, Mouse BCR.
Properties: pTyr360
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for BCR

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms BCR1, Breakpoint cluster region protein, D22S11, NY-REN-26, Renal carcinoma antigen NY-REN-26
Presentation Aff - Purified
Reactivity Hu, Ms
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight 142 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P11274
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y(p)-R-M) derived from Human Bcr (KLH-conjugated)
GeneID:
613
Property pTyr360
Application Western blot: 1:500~1:1000.
Background GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.
Concentration 1.0 mg/ml
General Readings
  1. Perazzona B, Lin H, Sun T, Wang Y, Arlinghaus R. Kinase domain mutants of Bcr enhance Bcr-Abl oncogenic effects. Oncogene. 2008 Apr 3;27(15):2208-14. Epub 2007 Oct 15. PubMed PMID: 17934518. (Free PMC Article available, 5 images available)
  2. Sun T, Campbell M, Gordon W, Arlinghaus RB. Preparation and application of antibodies to phosphoamino acid sequences. Biopolymers. 2001;60(1):61-75. PubMed PMID: 11376433.
  3. Wu Y, Liu J, Arlinghaus RB. Requirement of two specific tyrosine residues for the catalytic activity of Bcr serine/threonine kinase. Oncogene. 1998 Jan 8;16(1):141-6. PubMed PMID: 9467953.
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography using epitope-specific peptide
Buffer System:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse
Specificity
Specificity:
The antibody detects endogenous level of Bcr only when phosphorylated at tyrosine 360.

Accessory Products

Proteins and/or Positive Controls

Proteins for BCR (3 products)

Catalog No. Species Pres. Purity   Source  

BCR (transcript variant 2)

BCR Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

BCR

BCR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

BCR

BCR Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

Positive controls for BCR (2 products)

Catalog No. Species Pres. Purity   Source  

BCR 293T Cell Transient Overexpression Lysate(Denatured)

BCR 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

BCR overexpression lysate

BCR overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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