BB-MA1109 beta-Amyloid Protein antibody

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Mouse anti Human beta-Amyloid Protein AP-5


Product Description for beta-Amyloid Protein

Mouse anti Human beta-Amyloid Protein AP-5.
Presentation: Ascites
Product is tested for Paraffin Sections.

Properties for beta-Amyloid Protein

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Ascites
Reactivity Hu
Applications P
Clonality Monoclonal
Clone AP-5
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Synthetic β-amyloid peptide (1-40), conjugated to KLH.
Background Beta amyloid protein is 4.2-kD polypeptide. Glenner and Wong (1984) purified a protein derived from the twisted beta-pleated sheet fibrils present in cerebrovascular amyloidoses and in the amyloid plaques associated with Alzheimer disease. The proteins from both disorders have an identical 28-amino acid sequence. memory deficits in middle-aged Tg2576 mice are caused by the extracellular accumulation of a 56-kDa soluble amyloid-beta assembly. Amyloid beta protein (Abeta) deposition in the brain is a hallmark of Alzheimer's disease (AD).
General Readings
  1. Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature. 2006 Mar 16;440(7082):352-7. PubMed PMID: 16541076.
  2. Lorenzo A, Yuan M, Zhang Z, Paganetti PA, Sturchler-Pierrat C, Staufenbiel M, et al. Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat Neurosci. 2000 May;3(5):460-4. PubMed PMID: 10769385.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

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