GTX11313 beta I + II Tubulin antibody

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0.1 ml / €290.00

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Mouse anti Bovine, Chicken, Human, Mouse, Porcine, Rat beta I + II Tubulin JDR.3B8


Product Description for beta I + II Tubulin

Mouse anti Bovine, Chicken, Human, Mouse, Porcine, Rat beta I + II Tubulin JDR.3B8.
Presentation: Ascites
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for beta I + II Tubulin

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms beta-Tubulin, tubulin beta
Presentation Ascites
Reactivity Bov, Chk, Hu, Ms, Por, Rt
Applications ICC/IF, WB
Clonality Monoclonal
Clone JDR.3B8
Host Mouse
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

A chemically synthesized peptide corresponding to the carboxyl-terminal sequence of human beta-tubulin isotype II coupled to BSA.
Application IF, WB
Background Tubulin is the major building block of microtubules. This intracellular, cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement and the cytoskeleton. Except in the simplest eukaryotes, tubulin exists in all cells as a mixture of similar but not identical sets of alpha and beta tubulin polypeptides. Within either family, individual subunits diverge from each other (both within and across species) at less than 10% of the amino acid positions. The most extreme diversity is localized to the carboxy-terminal 15 residues. For beta-tubulin, five evolutionarily conserved isotype clones have been identified. These are almost totally conserved in the subunits utilized in the same cell types of different species with the exception of the hematopoietic beta tubulin which is highly divergent in sequence and which is not conserved between species. Research has been centered around the hypothesis that these beta tubulin isotypes contribute to unique functional properties. It has been reported that the different isotypes of tubulin differ from each other in their ability to polymerize into microtubules.
Buffer System:
Preservative: 0.1% Sodium Azide; Constituents: Raw Ascites
Cross-reacts with Human, Mouse, Rat, Cow, Chicken and Pig. Not yet tested in other species.

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