NB120-3358 Blood Group Lewis x antibody

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Mouse anti Human Blood Group Lewis x P12


Product Description for Blood Group Lewis x

Mouse anti Human Blood Group Lewis x P12.
Product is tested for Paraffin Sections.

Properties for Blood Group Lewis x

Product Category Primary Antibodies
Quantity 0.5 ml
Reactivity Hu
Applications P
Clonality Monoclonal
Clone P12
Host Mouse
Isotype IgM
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Fresh (non-cultured) placenta cell preparation (Human).
Background Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis a, Lewis b, Lewis x, Lewis y, and precursor type 1 chain antigens. This antibody belongs to the BG-7 group and detects the Lewis x (type 2 chain) blood-group antigen, which is expressed in gastrointestinal tumors, and lung cancers. It is found in crypt cells, which represent the proliferative compartment of the colonic mucosa, and strong homogeneous immunostaining is observed in most metastases and invasive cancer cells.
General Readings General / background references:Ree HJ et al. The Lewis X antigen. A new paraffin section marker for Reed-Sternberg cells. Cancer 67:1338-46 (1991). PubMed PMID: 1703918
IgM purified
Buffer System:
Preservative: 0.1% Sodium AzideConstituents: 1% BSA, 0.01M PBS
IgM purified
Cross-reacts with Human.Not yet tested in other species.

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