AM32301PU-N Blood Group Lewis Y antibody

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0.1 mg / €330.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human Blood Group Lewis Y A70-C/C8


Product Description for Blood Group Lewis Y

Mouse anti Human Blood Group Lewis Y A70-C/C8.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Frozen Sections.

Properties for Blood Group Lewis Y

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications C, ICC/IF, P
Clonality Monoclonal
Clone A70-C/C8
Host Mouse
Isotype IgM
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

A NZB/N Bom mouse was immunized with live cells of the Human colorectal carcinoma cell line Ls174T.
The isolated splenocytes of the mouse were fused with the myeloma cell line X63-Ag8.653.
Application Immunofluorescence. 
Immunohistochemistry on Frozen Sections

Immunohistochemistry on Paraffin Sections.
Recommended Dilutions: 1/50-1/500. Use 1/50 as a stating dilution.
Background Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins. Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking. Blood Group Lewis y is a carbohydrate determinant carried on both glycolipids and glycoproteins.
Concentration 0.1 mg/ml
Storage Store the antibody undiluted at 2-8°C. 
Shelf life: one year from despatch.
Buffer System:
0.05% Sodium Azide
Liquid purified Ig fraction
Species Reactivity
Species reactivity (tested):
This antibody clone A70-C/C8 recognize the epitope Fucα1-2Galβ1-4(Fucα1-3)GlcNAcβ1 and is therefore specific for blood group antigen LewisY.
The Monoclonal antibody has no cross-reactivity with the blood group H type 2 antigens or with Lea, sialyl-Lea, Lex , sialyl-Lex, Leb or Lec.

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