NBP1-22779 BOB1 (Wue-AC5) antibody

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0.5 ml / €400.00
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Quick Overview

Mouse anti Human, Mouse BOB1 (Wue-AC5) Wue-AC5

NBP1-22779

Product Description for BOB1 (Wue-AC5)

Mouse anti Human, Mouse BOB1 (Wue-AC5) Wue-AC5.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for BOB1 (Wue-AC5)

Product Category Primary Antibodies
Quantity 0.5 ml
Synonyms anti-B cell Oct binding protein 1 antibody, anti-B cell specific coactivator OBF 1 antibody, anti-B cell specific coactivator OBF1 antibody, anti-BOB 1 antibody, anti-OBF1 antibody, anti-OCAB antibody, anti-OCT binding factor 1 antibody, anti-POU domain class 2 associating factor 1 antib, anti-POU2AF1 antibody
Presentation Purified
Reactivity Hu, Ms
Applications P
Clonality Monoclonal
Clone Wue-AC5
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
A recombinant BOB.1/OBG.1 protein from c-terminal domain.
Application immunohistochemistry, ABC, immunohistochemistry 1:50-1:100
Background A novel 35kDa protein designated Bob1 (B cell Oct binding protein 1) is a lymphocyte specific transcription co activator protein. B cell specific transcription is mediated by octamer motifs found in immunoglobulin heavy and light chain gene promoters and in some immunoglobulin enhancers. These sites are bound by the B cell specific Oct1 and Oct2 transcription factors, and the B cell restricted co activator BOB.1/OBF.1. This protein interacts only with the Oct1/2 proteins through sub domains in the POU domain of the Oct1/2 proteins, enhancing their transcriptional efficacy. Although having no intrinsic capacity for DNA binding, Bob1 associates tightly with the octomer motif in the presence of Oct1 and Oct2. Bob1 is expressed at highest levels in spleen and peripheral blood leukocytes.
Storage Store at 4C. Do not freeze.
Format
Purification:
IgG purified
Buffer System:
Sodium Azide
Purity:
IgG purified
State:
Purified
Specificity
Specificity:
B cell specific octamer binding protein-1 (BOB-1) is a lymphocyte specific transcription co-activator protein. B-cell-specific transcription is mediated by octamer motifs found in immunoglobulin heavy and light chain gene promoters and in some immunoglobulin enhancers. These sites are bound by B cell specific Oct1 and Oct2 trascription factors and B-cell restricted co-activator BOB.1/OBF.1. This protein interacts only with Oct1/2 proteins. This antibody cross-reacts with human and mouse.
Species:
Human, Mouse

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