discontinued

AP21636PU-N Bovine Spongiform Encephalopathy / BSE (162-170) antibody

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0.1 mg / €350.00

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Rabbit anti Birds, Bovine, Sheep Bovine Spongiform Encephalopathy / BSE

Product Description for Bovine Spongiform Encephalopathy / BSE

Rabbit anti Birds, Bovine, Sheep Bovine Spongiform Encephalopathy / BSE.
Properties: (162-170)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Bovine Spongiform Encephalopathy / BSE

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Av, Bov, Sh
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Amino acids 162-170 of BSE protein
Property 162-170
Application Western blot: 0.5 - 2 µg/ml.
Recommended Positive Control: Recombinant fusion protein
Background BSE, also known as prion protein, is a membrane glycosylphosphatidylinositol-anchored glycoprotein belonging to the prion family of proteins and is responsible for several transmissible neurodegenerative spongiform encephalopathies. Though the exact function of BSE is not clear, reports suggest that it has a tendency to aggregate forming polymers known as rods and might act as a signaling neurotransmitter. BSE acts as a potent anti-apoptotic protein against BAX-mediated cell-death. Expression is higher in the brain of humans and animals infected with several degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), and transmissible mink encephalopathy (TME). Aberration in this protein is also associated with fatal familial insomnia and Huntington disease-like 1.
Concentration 0,5 mg/ml
General Readings
  1. Korth C, Stierli B, Streit P, Moser M, Schaller O, Fischer R, et al. Prion (PrPSc)-specific epitope defined by a monoclonal antibody. Nature. 1997 Nov 6;390(6655):74-7. PubMed PMID: 9363892.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide
State:
Liquid purified Ig fraction
Purified
Specificity
Specificity:
This antibody reacts to Bovine Spongiform Encephalopathy (BSE).
Species:
Sheep, Cow, Avian.

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