TA802672 BRCA1 / RNF53 antibody

BRCA1 mouse monoclonal antibody, clone OTI1C4 (formerly 1C4)

See related secondary antibodies

Search for all "BRCA1 / RNF53"

0.1 ml / €325.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Quick Overview

Mouse anti Human BRCA1 / RNF53 OTI1C4

Product Description for BRCA1 / RNF53

Mouse anti Human BRCA1 / RNF53 OTI1C4.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for BRCA1 / RNF53

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms Breast cancer type 1 susceptibility protein, RING finger protein 53
Presentation Purified
Reactivity Hu
Applications WB
Clonality Monoclonal
Clone OTI1C4
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P38398
Immunogen:
Human recombinant protein fragment corresponding to amino acids 1151-1473 of human BRCA1 (NP_009225) produced in E.coli.
GeneID:
672
Isotype control AM03095PU-N, SM10P (for use in human samples)
Application WB 1:2000
Background This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, D damage sensors, and sigl transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with R polymerase II, and through the C-termil domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, D repair of double-stranded breaks, and recombition. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Altertive splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many altertively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length tures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
Format
Purification:
Purified from mouse ascites fluids by affinity chromatography
Buffer System:
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for BRCA1 / RNF53 (5 products)

Catalog No. Species Pres. Purity   Source  

BRCA1 / RNF53

BRCA1 / RNF53 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

BRCA1 / RNF53

BRCA1 / RNF53 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

BRCA1 / RNF53

BRCA1 / RNF53 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BRCA1 / RNF53

BRCA1 / RNF53 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BRCA1 / RNF53

BRCA1 / RNF53 Human Purified > 95 % Insect cells
2 µg / €620.00
  Neuromics Antibodies
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