discontinued

DP3012 BRCA2 antibody

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0.5 mg / €270.00

Quick Overview

Rabbit anti Human BRCA2

DP3012

Product Description for BRCA2

Rabbit anti Human BRCA2.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation.

Properties for BRCA2

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms BRCA-2, FANCD, FANCD1
Presentation Purified
Reactivity Hu
Applications ICC/IF, IP
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Biomeda

Datasheet Extract

Immunogen
Immunogen:
A synthetic 24-mer peptide, aa 1324-1347, (YTAASRNSHNLEFDGSDSSKNDTV) from the human BRCA2 protein.
Application Immunofluorescence. Immunoprecipitation (Use Protein A): Ab 10µg/mg protein lysate. Recommended positive control: HeLa or MCF-7 Cells. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 1 mg/ml
General Readings
  1. Bernard-Gallon DJ; et al. International Journal of Cancer, 1997, 71(1):123-6.
  2. Coene E; et al. Nature Genetics, 1997 Jun
Storage Store the antibody at 4°C. Do not freeze! Shelf life: one year from despatch.
Format
State:
Purified
Specificity
Specificity:
BRCA2 is localized to chromosome 13q12-q13. Loss of heterozygosity of 13q is observed in 25% of sporadic breast tumors, which indicates that BRCA2 might be a tumor suppressor gene. BRCA2 confers only a low ovarian cancer risk. Reacts with HeLa or MCF-7 cells. Reacts with Human. Does not react with Mouse. Others not tested. Cellular Localization: Nuclear.

Mol. Wt. of antigen: 380kD

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