NBP1-30491 Breast carcinoma amplified sequence 3 antibody

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Rabbit anti Human Breast carcinoma amplified sequence 3

Product Description for Breast carcinoma amplified sequence 3

Rabbit anti Human Breast carcinoma amplified sequence 3.
Product is tested for Paraffin Sections.

Properties for Breast carcinoma amplified sequence 3

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms anti-BCAS-3 antibody, anti-BCAS3 antibody, anti-Breast Carcinoma Amplified Sequence 3 antibod, anti-GAOB1 antibody, anti-MAAB antibody
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
The immunogen for this product maps to a region between residue 870 and the C-terminus (residue 928) of human Breast Carcinoma Amplified Sequence 3 using the numbering given in entry BAB15156.1 (GeneID 54828).,
Add. information ,
Application This product is useful in Immunohistochemistry., Immunohistochemistry 1:100-1:500.
Background BCAS3 acts as an ERalpha coactivator in breast cancer cells. It has been demonstrated that PELP1, a newly described ERalpha coregulator, is recruited to BCAS3 chromatin and activates its expression. Analysis of the BCAS3 sequence for functional motifs and evidence from biochemical fractionation suggested that BCAS3 acts as a transcriptional coactivator. Results from chromatin immunoprecipitation, reporter assays, and expression studies further validated the coactivator function of BCAS3 for ERalpha. BCAS3 physically associated with histone H3 and histone acetyltransferase complex protein P/CAF and possessed histone acetyltransferase activity.
Storage Store at 4C. Do not freeze.
Immunogen affinity purified
Buffer System:
Tris-buffered Saline containing 0.1% BSA.
Gene ID 54828

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