AP15178PU-N BRSK1 (N-term) antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human BRSK1

Product Description for BRSK1

Rabbit anti Human BRSK1.
Properties: (N-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for BRSK1

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms BR serine/threonine-protein kinase 1, KIAA1811, SAD-B, SAD1, SAD1 kinase, Serine/threonine kinase SAD-B
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8TDC3
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BRSK1.
GeneID:
84446
Property N-term
Application ELISA: 1/1,000.
Western blotting: 1/100 - 1/500.
Background BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. Lu, R., et al., J. Biol. Chem. 279(30):31164-31170 (2004).
  2. Lizcano, J.M., et al., EMBO J. 23(4):833-843 (2004).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Buffer System:
PBS with 0.09% (W/V) sodium azide
State:
Liquid purified Ig
Purified
Specificity
Specificity:
This antibody reacts to BRSK1.
Species:
Human.
Gene ID 84446

Accessory Products

Proteins and/or Positive Controls

Proteins for BRSK1 (4 products)

Catalog No. Species Pres. Purity   Source  

BRSK1

BRSK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BRSK1

BRSK1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

BRSK1

BRSK1 Human
  Abnova Taiwan Corp.

BRSK1

BRSK1 Human
  Abnova Taiwan Corp.

Positive controls for BRSK1 (1 products)

Catalog No. Species Pres. Purity   Source  

BRSK1 overexpression lysate

BRSK1 overexpression lysate
0.1 mg / €495.00
  OriGene Technologies, Inc.
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