NB100-92279 BTF3L1 antibody

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0.1 mg / €420.00
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Rabbit anti Human, Mouse BTF3L1

NB100-92279

Product Description for BTF3L1

Rabbit anti Human, Mouse BTF3L1.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for BTF3L1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms anti-BTF3L1 antibody, anti-HUMBTFB antibody, anti-OCIF antibody, anti-OPG antibody, anti-TNFRSF11B antibody
Presentation Aff - Purified
Reactivity Hu, Ms
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, Western Blot, Western blot analysis of OPG (P25) antibody in extracts from 293 cells., Western Blot 1:500-1:1000, ELISA 1:5000-1:10000,
Background Bone morphogenesis and remodeling involve the formation of bone from osteoblasts and the resorption of bone by osteoclasts. The cytokine osteoprotegerin(OPG), also designated osteoclastogenesis inhibitory factor (OCIF), is known to inhibit osteoclast formation. A secreted glycoprotein, OPG is a member of the TNF receptor family that increases bone density and volume. OPG is thought to inhibit osteoclastogenesis by disrupting the cell-to-cell signaling between osteoblastic stromal cells and osteoclast progenitors. OPG is known to bind to TRAIL, a death domain-containing protein, and to inhibit TRAIL apoptosis in Jurkat cells. OPG also binds to osteoclast differentiation factor (ODF), also known as TRANCE/RANKL, a membrane-bound protein belonging to the TNF ligand family. Both TNFalpha and TNFbeta upregulate OPG expression, while the bone resorbing agent prostaglandin E2 downregulates OPG.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
OPG (P25) detects endogenous levels of OPG protein.
Species:
Human, Mouse

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