MAB4519 c-Myc antibody

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0.1 mg / €470.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human c-Myc 9E10

MAB4519

Product Description for c-Myc

Mouse anti Human c-Myc 9E10.
Presentation: HRP
Product is tested for Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot, Flow Cytometry.

Properties for c-Myc

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation HRP
Reactivity Hu
Applications F, IP, P, WB
Clonality Monoclonal
Clone 9E10
Host Mouse
Isotype IgG1
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer Abnova Taiwan Corp.
Manufacturer certificates ISO 13485:2003

Datasheet Extract

Immunogen
Immunogen:
A synthetic peptide corresponding to c-myc.
Remarks:
Gene Accession:
Add. information Mouse monoclonal antibody raised against synthetic peptide of c-Myc.
Application Flow Cyt,IHC-P,IP,WB
Storage Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light.This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Format
Label:
HRP
Buffer System:
In PBS (0.01% (w/v) thimerosal, 1% (w/v) high-grade protease free BSA)
Specificity
Specificity:
The antibody 9E10 may be used to detect the c-Myc tag.
The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
Species:
Human

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