discontinued

GTX24765 c-Raf (phospho S43) antibody

See related secondary antibodies

Search for all "c-Raf (phospho S43)"

50 µl / €290.00

Quick Overview

Rabbit anti Human, Mouse, Rat c-Raf (phospho S43)

GTX24765

Product Description for c-Raf (phospho S43)

Rabbit anti Human, Mouse, Rat c-Raf (phospho S43).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for c-Raf (phospho S43)

Product Category Primary Antibodies
Quantity 50 µl
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide (Human) derived from a region of human c-Raf that contains serine 43. The sequence is conserved in mouse and rat.
Application WB
Background The Raf family of serine/threonine-specific kinases is comprised of three members (A-Raf, B-Raf, and c-Raf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen-activated protein kinase (MAPK) pathway. c-Raf kinase (also known as Raf-1) is a key 74 kDa signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated phosphorylates MEK which in turn phosphorylates ERK. Serine 43 of c-Raf is phosphorylated by PKA, and is thought to negatively affect the ability of Ras to activate c-Raf.
Concentration 0.5 mg/ml
Format
Purification:
Immunogen affinity purified
Buffer System:
Preservative: 0.05% Sodium Azide; Constituents: PBS, 1.0mg/ml BSA (IgG, protease free). pH 7.3
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Specificity:
Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen), Rat (100% identity with immunogen) due to sequence homology. Not yet tested in other species.

Accessory Products

  • LinkedIn