GTX24765 c-Raf (phospho S43) antibody

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50 µl / €290.00

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Rabbit anti Human, Mouse, Rat c-Raf (phospho S43)


Product Description for c-Raf (phospho S43)

Rabbit anti Human, Mouse, Rat c-Raf (phospho S43).
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for c-Raf (phospho S43)

Product Category Primary Antibodies
Quantity 50 µl
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide (Human) derived from a region of human c-Raf that contains serine 43. The sequence is conserved in mouse and rat.
Application WB
Background The Raf family of serine/threonine-specific kinases is comprised of three members (A-Raf, B-Raf, and c-Raf) that play a critical role in regulating cell growth and differentiation, and couple growth factor receptor stimulation to nuclear transcription factors via the Ras/mitogen-activated protein kinase (MAPK) pathway. c-Raf kinase (also known as Raf-1) is a key 74 kDa signal transducer of multiple extracellular stimuli that is regulated by several pathways, and that once activated phosphorylates MEK which in turn phosphorylates ERK. Serine 43 of c-Raf is phosphorylated by PKA, and is thought to negatively affect the ability of Ras to activate c-Raf.
Concentration 0.5 mg/ml
Immunogen affinity purified
Buffer System:
Preservative: 0.05% Sodium Azide; Constituents: PBS, 1.0mg/ml BSA (IgG, protease free). pH 7.3
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen), Rat (100% identity with immunogen) due to sequence homology. Not yet tested in other species.

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