NB120-8778 C1 inactivator antibody

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Sheep anti Feline, Human C1 inactivator


Product Description for C1 inactivator

Sheep anti Feline, Human C1 inactivator.
Presentation: Purified

Properties for C1 inactivator

Product Category Primary Antibodies
Quantity 1 ml
Presentation Purified
Reactivity Fe, Hu
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Human C1 inactivator purified from plasma and shown to be homogeneous by SDS-PAGE.
Background C1 Inactivator is a plasma protein that plays a pivotal role in the regulation of the early stages of the classical complement pathway and the contact activation pathways. It is a protease inhibitor acting as a competitive substrate for its target enzymes. These cleave a 34 amino acid peptide, the remainder ofthe C1 inactivator molecule binding to the protease causing irreversible inhibition. C1 inactivator is one of only two known enzymic inhibitors of C1s, the other, nexin I, is far less effective.The mean serum concentration of C1 inactivator is 0.2g/L.C1 inactivator consists of a single heavily-glycosylated polypeptide chain with a molecular weight of104 kDa.
IgG purified
Buffer System:
Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA
IgG purified
Cross-reacts with Human, Dog and Cat.Does not cross-react with Rabbit, Rat, Horse, Mouse, Cow, Pig, Guinea pig or Chicken.Not yet tested in other species.

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