TA306232 C1QTNF2 (N-term) antibody

Rabbit Polyclonal CTRP2 Antibody

See related secondary antibodies

Search for all "C1QTNF2"

0.1 mg / €371.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse C1QTNF2

Product Description for C1QTNF2

Rabbit anti Human, Mouse C1QTNF2.
Properties: (N-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for C1QTNF2

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms CTRP2, Complement C1q tumor necrosis factor-related protein 2
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9BXJ5
Immunogen:
Murine CTRP2 (N-Terminus) Peptide (AP30249CP-N)
GeneID:
114898
Property N-term
Add. information Blocking peptide available: blocking peptide (AP30249CP-N)
Application ELISA.
Western Blot: CTRP2 antibody can be used for the detection of CTRP2 at 1 μg/ml. Caco-2 cell lysate can be used as positive control. These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Background Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).
General Readings
  1. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.
  2. Tsao TS, Lodish HF, Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol. 2002 Apr 12;440(2-3):213-21. PubMed PMID: 12007537.
  3. Wong GW, Wang J, Hug C, et al. A family of Acrp30/ adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.
  4. Shapiro L, Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol. 1998 Mar 12;8(6):335-8. PubMed PMID: 9512423.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography purified via peptide column
Buffer System:
PBS containing 0.02% sodium azide.
State:
Liquid purified Ig fraction
Aff - Purified
Specificity
Specificity:
CTRP2 antibody was raised against a 16 amino acid peptide from near the amino-terminus of human CTRP2.
Species:
Human, Mouse.

Accessory Products

Proteins and/or Positive Controls

Proteins for C1QTNF2 (3 products)

Catalog No. Species Pres. Purity   Source  

C1QTNF2

C1QTNF2 Human
  Abnova Taiwan Corp.

C1QTNF2

C1QTNF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

C1QTNF2

C1QTNF2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for C1QTNF2 (4 products)

Catalog No. Species Pres. Purity   Source  

C1QTNF2 293T Cell Transient Overexpression Lysate(Denatured)

C1QTNF2 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

C1QTNF2 HEK293 Cell Transient Overexpression Lysate (Non-Denatured)

C1QTNF2 HEK293 Cell Transient Overexpression Lysate (Non-Denatured) Transient overexpression cell lysate was tested with Anti-C1QTNF2 antibody (H00114898-M01) by Western Blots.
  Abnova Taiwan Corp.

C1QTNF2 overexpression lysate

C1QTNF2 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

CTRP2 Lysate

Western Blot: CTRP2 Lysate [NBL1-08343] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for C1QTNF2 Protein
  Novus Biologicals Inc.
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