NB120-8788 C4 binding protein antibody

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Sheep anti Human C4 binding protein


Product Description for C4 binding protein

Sheep anti Human C4 binding protein.
Presentation: Purified

Properties for C4 binding protein

Product Category Primary Antibodies
Quantity 1 ml
Presentation Purified
Reactivity Hu
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Human C4BP purified from plasma and shown to be homogeneous by SDS-PAGE.
Background C4-binding protein (C4BP) is a multimeric protein, synthesised in the liver. The most abundant form consists of seven alpha-chains (70kDa) and one beta-chain (45kDa) all linked by disulphide bonds to form the native protein with a molecular weight of 570kDa. It is is a plasma protein with a concentration of about 150mg/L in normal plasma.It is a component of the classical complement pathway. C4BP down regulates complement activity in two ways, it binds to C4b thus inhibiting the formation of C3-convertase (C4bC3a) and it accelerates the decay of existing convertases. C4BP acts as a cofactor in Factor I mediated C4b proteolysis. C4BP may also have a regulatory role in the coagulation system, by binding to Protein S. When bound toC4BP, Protein S is inactive.
IgG purified
Buffer System:
Glycine buffered saline pH7.4, 0.1% Sodium Azide, 0.1% EACA, 0.01% Benzamidine,1mM EDTA
IgG purified
Cross-reacts with Human.Not yet tested in other species.

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