TA328727 CAB3 antibody

Rabbit Polyclonal Anti-CaVbeta3

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Rabbit anti Human, Mouse, Rat CAB3


Product Description for CAB3

Rabbit anti Human, Mouse, Rat CAB3.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for CAB3

Product Category Primary Antibodies
Quantity 0.2 ml
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
Peptide (C)DRNWQRNRPWPKDSY, corresponding to amino acid residues 463-477 of rabbit CavÃ?3. Intracellular, C-terminus.
Application WB: 1:200-1:2000; IHC: 1:100-1:3000
Background The Ã?3 protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. Four Ã? isoforms were identified in mammalian genoms and they share some sequence as well as structure homology. The structure of CaVÃ?3 was recentely determined (as well as other CaVÃ? subunits; for review see reference 3). CaVÃ? subunits are cytoplasmic proteins, that bind the cytoplasmic face of the pore forming CaV a1 subunits. These interactions have profound effects on channel trafficing to the plasma membrane as well as on current parameters such as voltage dependent kinetics and interactions with modulatory proteins. CaVÃ?3 might interact with all the poreforming subunits that have been tested and in vivo is expressed in smooth muscle, trachea, aorta, lung and brain.
Affinity purified on immobilized antigen.
Buffer System:
Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

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