AP50726PU-N Calpain-6 (Center) antibody

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0.4 ml / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human Calpain-6

AP50726PU-N

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  • AP50726PU-N

Product Description for Calpain-6

Rabbit anti Human Calpain-6.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Calpain-6

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Molecular weight 74576 Da
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y6Q1
Immunogen:
KLH conjugated synthetic peptide between 289-319 amino acids from the Central region of human CAPN6
GeneID:
827
Property Center
Application ELISA: 1/1000.
Western blot: 1/100 - 1/500.
Immunohistochemistry on paraffin sections: 1/10 - 1/50.
Background Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
Concentration lot specific
General Readings
  1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  2. Secolin, R., et al. Psychiatr. Genet. 20(3):126-129(2010)
  3. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  4. Rho, S.B., et al. Cancer Lett. 271(2):306-313(2008)
  5. Rojas, F.J., et al. Mol. Hum. Reprod. 5(6):520-526(1999)
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Format
Purification:
Affinity Chromatography on Protein A
Buffer System:
PBS
Preservatives:
0.09% (W/V) sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody reacts to CAPN6.
Gene ID 827

Accessory Products

Proteins and/or Positive Controls

Proteins for Calpain-6 (1 products)

Catalog No. Species Pres. Purity   Source  

Calpain-6

Calpain-6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Positive controls for Calpain-6 (2 products)

Catalog No. Species Pres. Purity   Source  

Calpain 6 Lysate

Western Blot: Calpain 6 Lysate [NBL1-08682] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CAPN6
  Novus Biologicals Inc.

CAPN6 overexpression lysate

CAPN6 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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