NBP1-51945 CaMKII alpha antibody

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0.1 mg / €400.00
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Goat anti Human, Mouse CaMKII alpha


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  • NBP1-51945

Product Description for CaMKII alpha

Goat anti Human, Mouse CaMKII alpha.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Enzyme Immunoassay, Western blot / Immunoblot.

Properties for CaMKII alpha

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Ms
Applications E, P, WB
Clonality Polyclonal
Host Goat
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
internal region
Background Calcium/calmodulin-dependent protein kinase II (CaMKII) is a widely distributed protein kinase that regulates numerous physiological functions. Inhibitors of CaMKII are useful tools for investigating the CaMKII functions (1). The synapse contains densely localized and interacting proteins that enable it to adapt to changing inputs. A Ca2+-sensitive protein complex involved in the regulation of AMPA receptor synaptic plasticity. The complex is comprised of MUPPI, a multi-PDZ domain-containing protein; SynGAP, a synaptic GTPase-activating protein; and the Ca2+/calmodulin-dependent kinase CaMKII. In synapses of hippocampal neurons, SynGAP and CaMKII are brought together by direct physical interaction with the PDZ domains of MUPP1, and in this complex, SynGAP is phosphorylated. Ca2+CaM binding to CaMKII dissociates it from the MUPP1 complex, and Ca2+ entering via the NMDAR drives the dephosphorylation of SynGAP (2).
Concentration 0.5 mg/ml
Storage Store at -20C. Avoid freeze-thaw cycles.
Affinity purified
Buffer System:
0.5 mg/ml in Tris saline, pH7.3 with 0.5% bovine serum albumin.
Aff - Purified
Gene ID 815

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