NBP1-51543 CAMP / CAP18 antibody

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0.1 ml / €440.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti CAMP / CAP18 9H4C4

NBP1-51543

Product Description for CAMP / CAP18

Mouse anti CAMP / CAP18 9H4C4.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for CAMP / CAP18

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 18 kDa cationic antimicrobial protein, Antibacterial protein LL-37, CAP-18, Cathelicidin antimicrobial peptide, FALL-39, FALL39, HSD26, hCAP-18
Presentation Purified
Applications E
Clonality Monoclonal
Clone 9H4C4
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide of cAMP, conjugated to KLH.
Isotype control AM03095PU-N
Background Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Ascites
Buffer System:
Ascitic fluid containing 0.03% sodium azide.
State:
Purified
Gene ID 820

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