discontinued

NB100-1090 CAPON antibody

See related secondary antibodies

Search for all "CAPON"

0.1 mg / €400.00

Quick Overview

Goat anti Human CAPON

Product Description for CAPON

Goat anti Human CAPON.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Enzyme Immunoassay.

Properties for CAPON

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu
Applications E, P
Clonality Polyclonal
Host Goat
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetid peptide PSKTKYNLVDDGH, representing the N-Terminus of the human protein (residues 2-14), according to NP_055512.
Background **Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognize native protein in any application.

This is a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins.
Concentration 0.5 mg/ml
General Readings Jaffrey SR et al. CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron 20:115-24 (1998). PubMed PMID: 9459447
Format
Purification:
Immunogen affinity purified
Buffer System:
Tris saline containing [pH7.3] with 0.5% BSA
Purity:
Immunogen affinity purified
State:
Aff - Purified
Specificity
Species:
Expected to cross-react with Human, Rat and Mouse due to sequence homology. Not yet tested in other species.

Accessory Products

  • LinkedIn