AP00663PU-N Carboxy Methyl Lysine antibody

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1 mg / €690.00
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Goat anti Carboxy Methyl Lysine


Product Description for Carboxy Methyl Lysine

Goat anti Carboxy Methyl Lysine.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for Carboxy Methyl Lysine

Product Category Primary Antibodies
Quantity 1 mg
Synonyms CML, Carboxymethyl-lysine
Presentation Aff - Purified
Applications E, WB
Clonality Polyclonal
Host Goat
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Carboxymethylated Keyhole Limpet Hemocyanin (CML-KLH).
Prepared by the reaction of the protein with glyoxylic acid.
Add. information Centrifuge before opening to ensure complete recovery of vial contents.
Application Western Blot.
ELISA: 1/4,000-1/20,000.
Background Carboxymethyl Lysine is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.
Concentration 0.82 mg/ml (OD280nm, E0.1% = 1.35)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
CML-protein Sepharose Affinity Chromatography
Buffer System:
75mM PBS, pH 7.2 containing 75mM Sodium chloride and 0.5mM EDTA
0.02% Sodium Azide
Liquid purified IgG fraction
Aff - Purified
This antibody specifically binds to Carboxy Methyl Lysine / CML modified proteins.

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