Product Description for CARD12
Rabbit anti Human CARD12.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Presentation: Purified
Product is tested for Western blot / Immunoblot.
Properties for CARD12
Product Category | Primary Antibodies |
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Quantity | 0.1 mg |
Presentation | Purified |
Reactivity | Hu |
Applications | WB |
Clonality | Polyclonal |
Host | Rabbit |
Isotype | IgG |
Shipping to | Not USA/Canada |
PDF datasheet | View Datasheet |
Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
Immunogen |
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Application | Western Blot, This polyclonal antibody can be used for the detection of Ipaf by Western blot at 0.5 to 2 ug/ml. Human peripheral blood leukocyte (PBL) cell lysate can be used as positive control and a 110 kDa band can be detected. Anti-Ipaf is human specific., Western Blot 0.5-2 ug/ml, |
Background | Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kappaB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family (1). Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner (2,3). Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1. |
Storage | Store at 4C. Do not freeze. |
Format |
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Specificity |
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Accessory Products
Recommended Secondary Antibodies for CARD12 (9 products)
Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
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R1364AP |
Rabbit IgG (H+L chain) antibody |
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Goat | AP | Rb | E, WB | |||
Acris Antibodies GmbH | |||||||
R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
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Goat | Biotin | Rb | E, WB | |||
Acris Antibodies GmbH | |||||||
R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
![]() |
Goat | FITC | Rb | E, ICC/IF, WB | |||
Acris Antibodies GmbH | |||||||
R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
![]() |
Goat | HRP | Rb | E, P, WB | |||
Acris Antibodies GmbH | |||||||
R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
![]() |
Goat | TRITC | Rb | E, F, ICC/IF | |||
Acris Antibodies GmbH | |||||||
R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
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Donkey | PE | Rb | F | |||
Acris Antibodies GmbH | |||||||
R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
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Goat | Cy2 | |||||
Acris Antibodies GmbH | |||||||
R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
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Goat | Cy3 | |||||
Acris Antibodies GmbH | |||||||
R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
![]() |
Goat | Cy5 | |||||
Acris Antibodies GmbH |