NB100-94271 CARD12 antibody

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Rabbit anti Human CARD12

Product Description for CARD12

Rabbit anti Human CARD12.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for CARD12

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rabbit anti-Ipaf polyclonal antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human Ipaf (Genbank accession NP_067032).
Application Western Blot, This polyclonal antibody can be used for the detection of Ipaf by Western blot at 0.5 to 2 ug/ml. Human peripheral blood leukocyte (PBL) cell lysate can be used as positive control and a 110 kDa band can be detected. Anti-Ipaf is human specific., Western Blot 0.5-2 ug/ml,
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kappaB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family (1). Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner (2,3). Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
0.02% Sodium Azide
IgG purified

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