NB120-14305 cardiac Troponin I antibody

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Mouse anti cardiac Troponin I 247


Product Description for cardiac Troponin I

Mouse anti cardiac Troponin I 247.
Presentation: Purified
Product is tested for Enzyme Immunoassay.

Properties for cardiac Troponin I

Product Category Primary Antibodies
Quantity 0.2 mg
Presentation Purified
Applications E
Clonality Monoclonal
Clone 247
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified (free) cTnI or cTnI in ternary troponin complex, (Human).
Isotype control AM03095PU-N
General Readings General / background references:Marston SB & Redwood CS Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications. Circ Res 93:1170-8 (2003). PubMed PMID: 14670832
Sarko J & Pollack CV Cardiac troponins. J Emerg Med 23:57-65 (2002). PubMed PMID: 12217473
Gomes AV et al. The role of troponins in muscle contraction. IUBMB Life 54:323-33 (2002). PubMed PMID: 12665242
Hamm CW Acute coronary syndromes. The diagnostic role of troponins. Thromb Res 103 Suppl 1:S63-9 (2001). PubMed PMID: 11567671
Onuoha GN et al. Skeletal troponin-I release in orthopedic and soft tissue injuries. J Orthop Sci 6:11-5 (2001). PubMed PMID: 11289579
Bertinchant JP et al. Comparison of the diagnostic value of cardiac troponin I and T determinations for detecting early myocardial damage and the relationship with histological findings after isoprenaline-induced cardiac injury in rats. Clin Chim Acta 298:13-28 (2000). PubMed PMID: 10876001
Labugger R et al. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation 102:1221-6 (2000). PubMed PMID: 10982534
Reiffert SU et al. Stepwise subunit interaction changes by mono- and bisphosphorylation of cardiac troponin I. Biochemistry 37:13516-25 (1998). PubMed PMID: 9753437
Katrukha AG et al. Degradation of cardiac troponin I: implication for reliable immunodetection. Clin Chem 44:2433-40 (1998). PubMed PMID: 9836709
Wu AH et al. Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization. Clin Chem 44:1198-208 (1998). PubMed PMID: 9625043
Katrukha AG et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 43:1379-85 (1997). PubMed PMID: 9267317
Jaquet K et al. Pattern formation on cardiac troponin I by consecutive phosphorylation and dephosphorylation. Eur J Biochem 231:486-90 (1995). PubMed PMID: 7635159
Katus HA et al. Enzyme linked immuno assay of cardiac troponin T for the detection of acute myocardial infarction in patients. J Mol Cell Cardiol 21:1349-53 (1989). PubMed PMID: 2632816
Cummins B et al. Cardiac-specific troponin-I radioimmunoassay in the diagnosis of acute myocardial infarction. Am Heart J 113:1333-44 (1987). PubMed PMID: 3591601
Protein A purified
Buffer System:
Preservative: 0.1% Sodium AzideConstituents: PBS
Protein A purified
Cross-reacts with Human, Mouse, Rat, Cow, Cat, Dog, Goat, Pig and Rabbit.Not yet tested in other species.

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