GTX28962 Cardiotin antibody

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0.1 mg / €410.00

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Mouse anti Goat, Hamster, Human, Monkey, Mouse, Rabbit, Xenopus Cardiotin R2G


Product Description for Cardiotin

Mouse anti Goat, Hamster, Human, Monkey, Mouse, Rabbit, Xenopus Cardiotin R2G.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Western blot / Immunoblot, Paraffin Sections.

Properties for Cardiotin

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Gt, Hst, Hu, Mky, Ms, Rb, Xen
Applications C, P, WB
Clonality Monoclonal
Clone R2G
Host Mouse
Isotype IgM
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Total protein extract of chicken gizzard
Application IHC-Fr, IHC-P, WB
Background Cardiotin is a recently discovered, high molecular weight protein complex (300 kDa) located in the mitochondrial membrane. The cardiotin structure exists of subunits of 60 kDa and 100 kDa. Both subunits contain the same amino-terminal 14 amino-acid sequence, showing high homology to human skeletal muscle a-actinin, suggesting that the tetrameric configuration of the cardiotin protein structure is a transmembrane complex with the N-terminus at the cytoplasmic side of the membrane, able to interact with actin. During cardiac contractile dysfunction, the cardiotin distribution is affected in pathological cardiomyocytes i.e. chronic ischemic myocardium. This monoclonal antibody can be used in immunohistochemistry for the detection of a disturbed mitochondrial activity in cardiomyocytes i.e. during chronic ischemia or chronic atrial fibrillation.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Affinity purified with antigen.
Buffer System:
Preservative: 0.09% Sodium Azide; Constituents: PBS
Affinity purified with antigen.
Aff - Purified
Cross-reacts with Human, Rabbit, Mouse, Goat, Dog, Pig, Cat, Hamster, Monkey and Xenopus laevis. Not yet tested in other species.

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