SP6236P Caspase-13 / CASP-13 (aa 91-105) antibody

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Rabbit anti Human, Mouse, Rat Caspase-13 / CASP-13


Product Description for Caspase-13 / CASP-13

Rabbit anti Human, Mouse, Rat Caspase-13 / CASP-13.
Properties: (aa 91-105)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Caspase-13 / CASP-13

Product Category Primary Antibodies
Quantity 50 µg
Synonyms CASP 13, CASP13, Caspase 13, Caspase13, EC=3.4.22.-, ERICE, Evolutionary related interleukin-1-beta-converting enzyme
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer AnaSpec

Datasheet Extract

Rabbit anti-caspase-13 polyclonal antibody was raised against a peptide corresponding to amino acids 91 to 105 of human Acaspase-13 (1).
Property aa 91-105
Application Western blot (0.5 - 1 µg/ml). HL60 cell lysate can be used as positive control and a 43 kDa band should be detected. Other applications not tested. Optimal dilutions of this antibody are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
General Readings
  1. Humke., E. W. et al. (1998). ERICE, a n
Storage Store at +4oC or at -20oC if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Aff - Purified
This antibody recognises the caspase-13 (also known as ERICE).
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 ? Converting Enzyme) and caspase-13 (1). Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines (1).
Reacts with human, mouse and rat.

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