NB100-94239 Caspase 13 antibody

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Rabbit anti Human, Mouse, Rat Caspase 13

Product Description for Caspase 13

Rabbit anti Human, Mouse, Rat Caspase 13.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Caspase 13

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rabbit anti-caspase-13 polyclonal antibody was raised against a peptide corresponding to amino acids 91 to 105 of human Acaspase-13 (1).
Application Western Blot, This polyclonal antibody can be used for detection of AIF by Western blot at 0.5 to 1 ug/ml. HL60 cell lysate can be used as positive control and a 43 kDa band should be detected. It is human, mouse and rat reactive., Western Blot 0.5-1 ug/ml,
Background Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13 (1). Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines (1).
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
0.02% Sodium Azide
IgG purified
Casp-13 / ERICE
Human, Mouse, Rat

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