AP12574PU-N Caspase-6 pSer257 antibody

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0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human Caspase-6

AP12574PU-N

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  • AP12574PU-N

Product Description for Caspase-6

Rabbit anti Human Caspase-6.
Properties: pSer257
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Caspase-6

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P55212
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S257 of human caspase 6.
GeneID:
839
Property pSer257
Add. information Molecular weight: 33310 Da
Application ELISA: 1/1,000.
Western Blot: 1/100-1/500.
Immunohistochemistry: 1/50-1/100.
Background Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. Kalinin, A.E., et al., J. Invest. Dermatol. 124(1):46-55 (2005).
  2. Suzuki, A., et al., Oncogene 23(42):7067-7075 (2004).
  3. Horowitz, P.M., et al., J. Neurosci. 24(36):7895-7902 (2004).
  4. Schmeck, B., et al., Infect. Immun. 72(9):4940-4947 (2004).
  5. Mendez, E., et al., J. Virol. 78(16):8601-8608 (2004).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Buffer System:
PBS with 0.09% (W/V) Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Aff - Purified
Specificity
Specificity:
This antibody detects Caspase-6 pSer257.
Predicted to cross react with Mouse (100% Antigen Homology).
Species:
Human.
Gene ID 839
FocusOn and Reviews
FocusOns:

Accessory Products

Proteins and/or Positive Controls

Proteins for Caspase-6 (7 products)

Catalog No. Species Pres. Purity   Source  

Caspase-6 (N-term HIS tag, transcript variant alpha)

Caspase-6 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Caspase-6

Caspase-6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Caspase-6

Caspase-6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Caspase-6

Caspase-6 Human
  Abnova Taiwan Corp.

Caspase-6

Caspase-6 Human
  Abnova Taiwan Corp.

Caspase-6

Caspase-6 Human
  Abnova Taiwan Corp.

Caspase-6

Caspase-6 Human E. coli
  Kamiya Biomedical Company

Positive controls for Caspase-6 (3 products)

Catalog No. Species Pres. Purity   Source  

CASP6 overexpression lysate

CASP6 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

CASP6 overexpression lysate

CASP6 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

Caspase 6 Lysate

Western Blot: Caspase 6 Lysate [NBL1-08715] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for CASP6
  Novus Biologicals Inc.
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