AP07245PU-N CBX4 / PC2 (95-107) antibody

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Search for all "CBX4 / PC2"

50 µg / €380.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human CBX4 / PC2

Product Description for CBX4 / PC2

Rabbit anti Human CBX4 / PC2.
Properties: (95-107)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot, Paraffin Sections.

Properties for CBX4 / PC2

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog
Presentation Aff - Purified
Reactivity Hu
Applications E, ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O00257
Immunogen:
Synthetic peptide from aa 95-107 of human CBX4
GeneID:
8535
Property 95-107
Application ELISA: 1/10000 - 1/40000.
Immunofluorescence: 1/100 - 1/400.
Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
Western Blot: 1/1000 - 1/4000.
Background PC2 is the human homolog of the Drosophila 'Polycomb' (Pc) protein which has been identified as a gene family member associated with a cellular memory system that is responsible for the inheritance of gene activity by progeny cells. The human Pc homolog gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homolog, CBX2 (hPc1). However, the hPc2 and CBX2/hPc1 proteins are shown to colocalize in interphase nuclei of human U-2 OS osteosarcoma cells, suggesting that the proteins are part of a common protein complex. The human protein is believed to function as a repressor of proto-oncogene activity and that interference with hPc2 function can lead to derepression of proto-oncogene transcription and subsequently to cellular transformation. Other reports describe PC2 as a protein that has SUMO E3 activity for the corepressors CtBP and CtBP2.
Concentration 1.36 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Immunoaffinity Chromatography
Buffer System:
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide
State:
Liquid purified Ig
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, Mouse
Specificity
Specificity:
This antibody reacts to aa 95-107 of PC2 protein.
Gene ID 8535

Accessory Products

Proteins and/or Positive Controls

Proteins for CBX4 / PC2 (4 products)

Catalog No. Species Pres. Purity   Source  

CBX4 / PC2

CBX4 / PC2 Human Purified
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human Purified
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human
  Abnova Taiwan Corp.

Positive controls for CBX4 / PC2 (1 products)

Catalog No. Species Pres. Purity   Source  

CBX4 293T Cell Transient Overexpression Lysate(Denatured)

CBX4 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
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