Product Description for CBX4 / PC2
Rabbit anti Human, Mouse CBX4 / PC2.
Properties: (N-term)
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties: (N-term)
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.
Properties for CBX4 / PC2
| Product Category | Primary Antibodies |
|---|---|
| Target Category | |
| Quantity | 0.4 ml |
| Synonyms | Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog |
| Presentation | Purified |
| Reactivity | Hu, Ms |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | Ig |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Polyclonal Antibodies (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Property | N-term |
| Add. information | Predicted Molecular weight: 61228 Da |
| Application | ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. |
| Background | CBX4 is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of proper expression patterns of developmental master regulators; changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system responsible for the inheritance of gene activity by progeny cells. It participates in maintaining the transcriptionally repressive state of genes. CBX4 is part of acomplex that acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. CBX4 is an E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | lot specific |
| General Readings |
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| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 8535 |
Accessory Products
Proteins and/or Positive Controls
Proteins for CBX4 / PC2 (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00008535-P01 |
CBX4 / PC2 |
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|
Human | Purified | |||||
| Abnova Taiwan Corp. | |||||||
| H00008535-P01-25 |
CBX4 / PC2 |
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|
|
Human | Purified | |||||
| Abnova Taiwan Corp. | |||||||
| P1124 |
CBX4 / PC2 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
| P1125 |
CBX4 / PC2 |
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|
|
Human | ||||||
| Abnova Taiwan Corp. | |||||||
Positive controls for CBX4 / PC2 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00008535-T01 |
CBX4 293T Cell Transient Overexpression Lysate(Denatured) |
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|
|||||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for CBX4 / PC2 (9 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | Rb | E, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | Rb | E, ICC/IF, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | Rb | E, P, WB | |||
| OriGene Technologies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | Rb | E, F, ICC/IF | |||
| OriGene Technologies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | Rb | F | |||
| OriGene Technologies GmbH | |||||||
| R1458C2 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy2 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C3 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
|
Goat | Cy3 | |||||
| OriGene Technologies GmbH | |||||||
| R1458C5 |
Rabbit IgG (H+L chain, adsorbed) antibody |
||||||
|
Goat | Cy5 | |||||
| OriGene Technologies GmbH | |||||||
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