AP12234PU-N CBX4 / PC2 (C-term) antibody

See related secondary antibodies

Search for all "CBX4 / PC2"

0.4 ml / €370.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human CBX4 / PC2

Product Description for CBX4 / PC2

Rabbit anti Human CBX4 / PC2.
Properties: (C-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for CBX4 / PC2

Product Category Primary Antibodies
Target Category
Quantity 0.4 ml
Synonyms Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O00257
Immunogen:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBX4.
GeneID:
8535
Property C-term
Add. information Predicted Molecular weight: 61228 Da
Application ELISA: 1/1,000.
Western Blot: 1/100-1/500.
Background Chromobox homolog 4 (CBX4 or Pc2) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression pf PcG proteins have been associated with cancer. CBX4 is a part of the cellular memory system that is responsible for the inheritance of gene activity by progeny cells. CBX4 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain. It was reported that Pc2 is involved in sumoylation process by recruiting SUMO E1 and E2, and Pc2 is actually SUMO E3 during sumoylation events. CBX4 expression is ubiquitous.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. Claudius Vincenz, et al. PNAS, Oct 2008; 105: 16572 - 16577. (Applications: WB)
  2. Jones, Marius C., et al. PNAS 2006 Oct 31;103(44):16272-16277. (Applications: WB)
  3. Kagey, M.H., et al., Cell 113(1):127-137 (2003).
  4. Satijn, D.P., et al., Mol. Cell. Biol. 17(10):6076-6086 (1997).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Buffer System:
PBS with 0.09% (W/V) Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Purified
Specificity
Specificity:
This antibody is specific to CBX4 (C-term).
Species:
Human.
Gene ID 8535

Accessory Products

Proteins and/or Positive Controls

Proteins for CBX4 / PC2 (4 products)

Catalog No. Species Pres. Purity   Source  

CBX4 / PC2

CBX4 / PC2 Human Purified
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human Purified
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human
  Abnova Taiwan Corp.

CBX4 / PC2

CBX4 / PC2 Human
  Abnova Taiwan Corp.

Positive controls for CBX4 / PC2 (1 products)

Catalog No. Species Pres. Purity   Source  

CBX4 293T Cell Transient Overexpression Lysate(Denatured)

CBX4 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.
  • LinkedIn