NB100-92491 CCR5 antibody

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0.1 mg / €420.00

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Rabbit anti Human, Mouse, Rat CCR5

Product Description for CCR5

Rabbit anti Human, Mouse, Rat CCR5.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for CCR5

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Anti-CCCKR5 antibody, Anti-CCR5 antibody, anti-CC-CKR-5 antibody, anti-CD195 antibody, anti-CKR-5 antibody, anti-CKR5 antibody, anti-CMKBR5 antibody, anti-FLJ78003 antibody, anti-IDDM22 antibody
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Add. information Research Areas: Immunology
Application ELISA, immunohistochemistry, Western Blot, Western blot analysis of p-CCR5 (S349) antibody in extracts from RAW264.7 cell treated with PMA 125ng/ml 30', ELISA 1:10000-1:20000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,
Background The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Immunogen affinity purified
Aff - Purified
p-CCR5 (S349) detects endogenous levels of p-CCR5 (S349) protein.
Human, Mouse, Rat

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