AP21158PU-N CCS / SOD4 antibody

See related secondary antibodies

Search for all "CCS / SOD4"

0.1 mg / €350.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human CCS / SOD4

Product Description for CCS / SOD4

Rabbit anti Human CCS / SOD4.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for CCS / SOD4

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms SOD-4, Superoxide Dismutase Copper Chaperone
Presentation Aff - Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Molecular weight ~ 32 kDa
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O14618
GeneID:
9973
Application Western Blot: 1/500 - 1/1000.
Background Cu-Zn superoxide dismutase-1 (SOD-1) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Copper chaperone for SOD-1 (CCS) is essential for the incorporation of copper into SOD-1, and therefore is necessary for its enzymatic activity. CCS prevents copper ions from binding to intracellular copper scavengers and provides the SOD-1 enzyme with the necessary copper cofactor. CCS escorts copper only to SOD-1 and fails to deliver copper to proteins in the mitochondria, nucleus or secretory pathway. CCS interacts with both wildtype and mutated forms of SOD-1 through CCS domains that are homologous in SOD-1. CCS exists as a homodimer that may form a heterodimer with SOD-1 during copper loading. While many tissues express CCS, the chaperone is most abundant in the kidney, liver and Purkinje cells in the neuropil of the central nervous system. The gene for CCS maps to human chromosome 11q13.
Concentration 1.0 mg/ml
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity chromatography (> 95% (by SDS-PAGE)
Buffer System:
Phosphate buffered saline (PBS), pH 7.2.
Preservatives:
0.05% sodium azide
State:
Liquid purified Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human.
Specificity
Specificity:
This antibody detects endogenous levels of CCCS protein.
(region surrounding Pro271)
Gene ID 9973

Accessory Products

Proteins and/or Positive Controls

Proteins for CCS / SOD4 (8 products)

Catalog No. Species Pres. Purity   Source  

CCS / SOD4 (1-274, His-tag)

CCS / SOD4 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  OriGene Technologies GmbH

CCS / SOD4 (1-274, His-tag)

CCS / SOD4 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  OriGene Technologies GmbH

CCS / SOD4

CCS / SOD4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

CCS / SOD4

CCS / SOD4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

CCS / SOD4

CCS / SOD4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CCS / SOD4

CCS / SOD4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CCS / SOD4

CCS / SOD4 Human Purified
  Novus Biologicals Inc.

CCS / SOD4

CCS / SOD4 Human Purified
  Novus Biologicals Inc.

Positive controls for CCS / SOD4 (2 products)

Catalog No. Species Pres. Purity   Source  

CCS 293T Cell Transient Overexpression Lysate(Denatured)

CCS 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

CCS overexpression lysate

CCS overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
  • LinkedIn