NB100-77666R CD105 (MJ7/18) antibody

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Rat anti Mouse CD105 (MJ7/18) MJ7/18


Product Description for CD105 (MJ7/18)

Rat anti Mouse CD105 (MJ7/18) MJ7/18.
Presentation: DyLight549
Product is tested for Frozen Sections, Flow Cytometry, Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot.

Properties for CD105 (MJ7/18)

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms anti-Enoglin antibody
Presentation DyLight549
Reactivity Ms
Applications C, F, IP, P, WB
Clonality Monoclonal
Clone MJ7/18
Host Rat
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

inflamed mouse skin
Add. information Research Areas: Stem Cell Markers, Immunology, Cellular Markers
Application flow cytometry / FACS analysis, Immunohistochemistry-Frozen, immunoprecipitation, Western Blot, Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume. Immunohistochemistry-frozen section. It is recommended that the reagent be titrated for optimal performance for each application., flow cytometry / FACS analysis , immunoprecipitation , Western Blot , Immunohistochemistry-Frozen
Background CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and up-regulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF- szlig1, TGF- szlig3 and modulates TGF- szlig signaling by interacting with TGF- szlig receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2 and -7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging, prognosis, as well as has therapeutic potential for some solid tumors and other angiogenic diseases.
Concentration 1 mg/ml
Storage Store at 4C. Do not freeze.
DyLight 549
Immunogen affinity purified
Buffer System:
No Preservative
Immunogen affinity purified
CD105 (MJ7/18)

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