TA328659 CD111 / Nectin 1 antibody

Rabbit Polyclonal Anti-Nectin-1 (extracellular)

See related secondary antibodies

Search for all "CD111 / Nectin 1"

0.2 ml / €622.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat CD111 / Nectin 1

TA328659

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Product Description for CD111 / Nectin 1

Rabbit anti Human, Mouse, Rat CD111 / Nectin 1.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for CD111 / Nectin 1

Product Category Primary Antibodies
Target Category
Quantity 0.2 ml
Synonyms HVEC, Herpes virus entry mediator C, Herpesvirus Ig-like receptor, Nectin-1, PRR1, PVRL1, Poliovirus receptor-related protein 1
Presentation Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q15223
Immunogen:
Peptide (C)GKPPSVVSWETRLK, corresponding to amino acid residues 177- 190 of human nectin-1. Extracellular, N-terminus.
GeneID:
5818
Application WB: 1:200-1:2000; IHC: 1:100-1:3
000; FC: 1:50-1:600;
Background Nectins, which were origilly identified as virus receptors, are members of the cell-cell adhesion molecule (CAM) family. They are Ca2+-independent immunoglobulin-like CAMs. The nectin family comprises four members, nectin-1, nectin-2, nectin-3 and nectin-4, which are encoded by the PVRL1, PVRL2, PVRL3 and PVRL4 genes, respectively. In the central nervous system, these cell adhesion molecules aggregate in formations, termed puncta adherentia junctions, which are mechanical adhesive sites that connect pre- and postsyptic membranes. All nectins contain an extracellular region with three immunoglobulin-like loops (one V type and two C2 types), a single membrane-spanning region and a cytoplasmic tail. Nectins directly bind afadin, an F-actin-binding protein, through their cytoplasmic tails. Nectin-1 is expressed at cell-cell junctions in human and mouse epidermis. In mice lacking the gene encoding nectin-1 (Pvrl1-/- mice), the expression of loricrin, a differentiation marker and a major component of cornified cell envelopes in the epidermis, is downregulated and newborn pups have a shiny and slightly reddish skin. Mutations in human PVRL1 are implicated in cleft lip or palate-ectodermal dysplasia syndromes, which includes Zlotogora–Ogur syndrome and Margarita Island ectodermal dysplasia. Both of these are autosomal recessive disorders that are clinically characterized by unusual facial appearance, dental anomalies, hypotrichosis, palmoplantar hyperkeratosis and onychodysplasia, syndactyly, cleft lip or palate, and in some cases, mental retardation.
Format
Purification:
Affinity purified on immobilized antigen.
Buffer System:
Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for CD111 / Nectin 1 (9 products)

Catalog No. Species Pres. Purity   Source  

CD111 / Nectin 1 (transcript variant 1)

CD111 / Nectin 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €438.00
  OriGene Technologies, Inc.

CD111 / Nectin 1 (transcript variant 1)

CD111 / Nectin 1 E. coli > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

CD111 / Nectin 1

CD111 / Nectin 1 Human
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human > 90 % Sf9-Baculovirus
  Virusys Corporation

Positive controls for CD111 / Nectin 1 (5 products)

Catalog No. Species Pres. Purity   Source  

PVRL1 293T Cell Transient Overexpression Lysate(Denatured)

PVRL1 293T Cell Transient Overexpression Lysate(Denatured)
  Abnova Taiwan Corp.

PVRL1 Lysate

Western Blot: PVRL1 Lysate [NBL1-15005] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for PVRL1
  Novus Biologicals Inc.

PVRL1 overexpression lysate

PVRL1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

PVRL1 overexpression lysate

PVRL1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

PVRL1 overexpression lysate

PVRL1 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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